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maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 1I91
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11390(2-(3-Hydroxyphenyl)-3-(4-morpholinylmethyl)-2H-thi...)
Affinity DataKi:  0.150nM ΔG°:  -58.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11390(2-(3-Hydroxyphenyl)-3-(4-morpholinylmethyl)-2H-thi...)
Affinity DataIC50:  1.15nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11390(2-(3-Hydroxyphenyl)-3-(4-morpholinylmethyl)-2H-thi...)
Affinity DataIC50:  1.20nMAssay Description:Concentration which produces 50% inhibition of human Carbonic anhydrase IIMore data for this Ligand-Target Pair