TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS) isoenzyme.More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
Affinity DataKi: 610nM ΔG°: -36.1kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
Affinity DataKi: 4.55E+3nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against recombinant human (neuronal nitric oxide synthase) n-NOSMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Concentration required to inhibit neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of neuronal nitric oxide synthase (nNOS) in miceMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of cloned (from RNA) human Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Compound was tested in vitro for inhibitory activity against nNOS(constitutive isoform found in neurons)More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against isomeric form of Neuronal nitric oxide synthase measured by citrulline assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human nNOS by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant rat nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of rat nNOS expressed in HEK293T cells preincubated for 30 mins prior A23187-induced activation measured after 6 hrs by Griess assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of wild type rat nNOS by hemoglobin capture assayMore data for this Ligand-Target Pair