Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 1NFW
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM12596(4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1...)
Affinity DataKi:  1.10nM ΔG°:  -50.6kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM12596(4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM12596(4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity (in vitro) of the compound towards human Coagulation factor X was determined at 5 mg/kg peroral doseMore data for this Ligand-Target Pair