Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) for PDB: 1NZ7
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15819(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  63nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15819(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  76nM ΔG°:  -40.2kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15819(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  76nMAssay Description:Inhibitory activity against protein-tyrosine phosphatase 1B (PTP 1B) was determinedMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50183057(CHEMBL3818765)
Affinity DataKi:  76nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM15819(1:1 mixture of diastereomers | 2-[(4-{2-[(4-{[(1S)...)
Affinity DataKi:  77nMAssay Description:Inhibitory activity against Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair