Found 5 Enz. Inhib. hit(s) for PDB: 1ODW TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataKi: 100nM ΔG°: -41.6kJ/mole IC50: 125nMpH: 5.5 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 100nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:In vitro inhibition of HIV-1 protease.More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 125nMpH: 5.5 T: 2°CAssay Description:IC50 values are determined by inhibition of the cleavage of the peptidic substrate [V-S-Q-N-(beta-naphthylalanine)-P-I-V]. The IC50 value represents ...More data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of HIV protease cleavage of V-S-Q-N-(b-naphthylalanine)-P-I-VMore data for this Ligand-Target Pair
