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Found 3 Enz. Inhib. hit(s) for PDB: 1QDQ
TargetCathepsin B(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM16509((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...)
Affinity DataIC50:  4.40nMpH: 5.5 T: 2°CAssay Description:Inhibition of cathepsin B was assayed in reaction buffer (50 mM NaOAc-HCl, 2 mM dithiothreitol, 2 mM EDTA, pH 5.5) containing 20 µM substrate an...More data for this Ligand-Target Pair
TargetCathepsin B(Bos taurus (bovine))
Osaka University Of Pharmaceutical Sciences

LigandPNGBDBM16509((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...)
Affinity DataIC50:  38nMpH: 6.0 T: 2°CAssay Description:Inhibitory activities (IC50, concentration of 50% inhibition) of compounds for bovine CB in vitro were determined by monitoring the cleavage of fluor...More data for this Ligand-Target Pair
TargetCathepsin B(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM16509((2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarb...)
Affinity DataIC50:  7.56E+3nMAssay Description:Inhibition of human liver cathepsin B after 30 mins by fluorometric end-point assayMore data for this Ligand-Target Pair