Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) for PDB: 1QXK
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13987(1:1 racemic mixture | 2-{4-[2-acetamido-2-({4-[3-h...)
Affinity DataKi:  7.94E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50308851((S)-2-(4-(2-acetamido-3-(4-(3-hydroxy-2-(methoxyca...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13987(1:1 racemic mixture | 2-{4-[2-acetamido-2-({4-[3-h...)
Affinity DataKi:  9.00E+3nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50308851((S)-2-(4-(2-acetamido-3-(4-(3-hydroxy-2-(methoxyca...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50308851((S)-2-(4-(2-acetamido-3-(4-(3-hydroxy-2-(methoxyca...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair