Target3-phosphoinositide-dependent protein kinase 1 [51-359,V143T,T222A](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [51-359,V143T](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [51-359,L159M](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [51-359,E166D](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 610nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [51-359,T222A](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 734nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [51-359,A162V](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 743nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of wild type PDK1 (unknown origin)More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [51-359](Homo sapiens (Human))
University Of Dundee
University Of Dundee
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataKd: 700nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataKd: 700nMAssay Description:Binding constant for PDPK1 kinase domainMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University College Cork
Curated by ChEMBL
University College Cork
Curated by ChEMBL
Affinity DataKd: 700nMAssay Description:Binding constant for full-length PDPK1More data for this Ligand-Target Pair