TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of human PTP1B catalytic domain expressed in Escherichia coli assessed as pNPP hydrolysis measured every 30 secs for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair