TargetTyrosine-protein phosphatase non-receptor type 1 [V113L,M114V](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 29nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [G117E](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 32nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 39nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [V113I](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 39nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of flag-tagged human PTP1B (1 to 298 residues) catalytic domain expressed in Escherichia coli BL21 cells using fluorescein diphosphate as ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [M114V](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 45nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1 [L119V](Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Merck Frosst Center For Therapeutic Research
Affinity DataIC50: 142nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair