Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) for PDB: 2HY0
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195213(3-(5-(piperidin-1-ylmethyl)-1H-indol-2-yl)-6-(1H-p...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of human CHEK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50195213(3-(5-(piperidin-1-ylmethyl)-1H-indol-2-yl)-6-(1H-p...)
Affinity DataEC50:  97nMAssay Description:Release of camptothecin-induced cell cycle arrest in NCI-H1299 cells mediated by CHEK1 inhibitionMore data for this Ligand-Target Pair