Found 15 Enz. Inhib. hit(s) for PDB: 2IMA 
Affinity DataKi: 300nMAssay Description:Inhibition of Clostridium botulinum toxin BoNT/A light chainMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 300nMAssay Description:Competitive inhibition of Clostridium botulinum truncated BoNT/A light chain (1-425) using truncated SNAP 25 (141-206) peptide as substrate by LC/MS ...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Competitive inhibition of Clostridium botulinum BoNT/A Hall A hyper protease light chain (1-425aa) using SNAP-66mer (141-206aa) as substrate by FRET ...More data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMAssay Description:Competitive inhibition of Clostridium botulinum full length BoNT/A light chain (1-448) using truncated SNAP 25 (141-206) peptide as substrate by LC/M...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMpH: 7.4 T: 2°CAssay Description:Recombinant BoNT LC/A activity was measured in black 96-well microtiter plates by use of a Molecular Devices (Sunnyvale, CA) SpectraMax GeminiEM plat...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of Clostridium botulinum toxin BoNT/A light chainMore data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of Clostridium botulinum BoNT/AMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of Clostridium botulinum recombinant BoNT/A light chain using N-terminal acetylated, C-terminal aminated SNAP-25 (187-203) as substrate by...More data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of clostridium botulinum Botulinum neurotoxin type A using SNAPide as substrate by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMpH: 7.4 T: 2°CAssay Description:Recombinant BoNT LC/A activity was measured in black 96-well microtiter plates by use of a Molecular Devices (Sunnyvale, CA) SpectraMax GeminiEM plat...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of Clostridium botulinum BoNT/AMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Reactions between recombinant BoNTA-LC and fluorescent peptide substrate were carried out in 96-well microplates. Reaction progress was measured cont...More data for this Ligand-Target Pair
Affinity DataIC50: >2.90E+4nMAssay Description:Inhibition of Clostridium botulinum neurotoxin A light chain by HPLC-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of Clostridium botulinum BoNT/A expressed in rat spinal cord neuron assessed as decrease in SNAP25 cleavage up to 600 uMMore data for this Ligand-Target Pair
