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Found 3 Enz. Inhib. hit(s) for PDB: 2IWS
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68260(Microlactone, 15f cis)
Affinity DataIC50:  500nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68260(Microlactone, 15f cis)
Affinity DataIC50:  850nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
University Of Nottingham

LigandPNGBDBM68260(Microlactone, 15f cis)
Affinity DataIC50:  2.40E+3nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair