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Found 2 Enz. Inhib. hit(s) for PDB: 2JAJ
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-Universitaet Zu Kiel

US Patent
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)
Affinity DataKi:  1.30E+4nM IC50:  2.90E+4nMpH: 7.4Assay Description:This assay was used to determine the inhibiting effect of the inhibitors in a concentration of 1 mM. A standard incubation mixture consisted of 75 &#...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Christian-Albrechts-Universitaet Zu Kiel

US Patent
LigandPNGBDBM141899(US8921421, L-257 | hDDAH inhibitor, 2a)
Affinity DataKi:  1.30E+4nM ΔG°:  -29.0kJ/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair