Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) for PDB: 2QP8
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227337(CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227337(CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227337(CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-...)
Affinity DataIC50:  106nMAssay Description:Inhibition of human BACE1 assessed as amyloid beta 40 production in human HEK293 cells by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50227337(CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-...)
Affinity DataIC50:  106nMAssay Description:Inhibition of BACE1 in HEK293 cells transfected with human APP cDNA containing Swedish ad London FAD mutant assessed as inhibition of amyloid beta 1-...More data for this Ligand-Target Pair