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Found 5 Enz. Inhib. hit(s) for PDB: 2VTD
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataIC50:  8.50E+4nMMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataIC50:  8.50E+4nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 13 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataKd:  5.50E+3nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 56 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
University Of Ljubljana

LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 9 by 1H/13C-HSQC 2D NMR spectroscopyMore data for this Ligand-Target Pair