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Found 12 Enz. Inhib. hit(s) for PDB: 3GUG
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  5.90nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  5.90nMAssay Description:Inhibition of human wild type AKR1C1 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  6.60nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Phe311Ala mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  7nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Phe311Leu mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [H222S](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  70nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [L54V](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  85nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [L306A](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1 [L308A](Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  2.80E+3nM ΔG°:  -31.7kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataKi:  9.40E+4nM ΔG°:  -23.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University

LigandPNGBDBM26269(3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 20-alpha HSD (unknown origin)More data for this Ligand-Target Pair