Found 75 Enz. Inhib. hit(s) for PDB: 3ML5 TargetCarbonic anhydrase 1/12/13/14/2/3/4/5A, mitochondrial/5B, mitochondrial/6/7/9(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Compound was evaluated for the inhibition of Carbonic anhydrase (Non competitive)More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 2nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 7 + BH(Homo sapiens (Human))
University Of Tampere And Tampere University Hospital
University Of Tampere And Tampere University Hospital
Affinity DataKi: 2.30nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -49.1kJ/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase (CA) inhibition against hCA II and V11 with synthesized compounds 2-8.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 7 + BH(Homo sapiens (Human))
University Of Tampere And Tampere University Hospital
University Of Tampere And Tampere University Hospital
Affinity DataKi: 2.5nMpH: 7.5Assay Description:Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -45.6kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 pre-incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant CA-7 after 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of carbonic anhydrase-7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -49.1kJ/moleT: 2°CAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins at room temperature/6 hrs at 4 deg C by stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant membrane bound CA7 expressed in Escherichia coli preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 expressed in Escherichia coli BL21 (DE3) by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant CAH7More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins at pH 7.5 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant CA7 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human full length carbonic anhydrase 7 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant full length CA7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of full length human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant CA7 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant full length CA7-mediated CO2 hydration preincubated for 15 mins by stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 expressed in Escherichia coli assessed as reduction in CO2 hydration preincubated for 15 mins pr...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase-7 using CO2 as substrate preincubated for 10 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase-7 assessed as reduction in enzyme-catalyzed hydration activity using CO2 as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 10 mins by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 assessed as CO2 hydration preincubated for 15 mins prior to testing measured for 10 to 100 secs ...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydrat...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
