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Found 9 Enz. Inhib. hit(s) for PDB: 3NTY
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  0.850nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Phe311Leu mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  0.860nMAssay Description:Inhibition of human wild type AKR1C1 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.20nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Leu308Ala mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.5nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Phe311Ala mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.70nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Leu308Val mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  4.80nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Leu54Val mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  21nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  70nMAssay Description:Competitive inhibition of human recombinant AKR1C1 Leu306Ala mutant by fluorescence assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human AKR1C1-mediated progesterone metabolism expressed in bovine aortic endothelial cells assessed as formation of 20alpha-hydroxyprog...More data for this Ligand-Target Pair