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Found 2 Enz. Inhib. hit(s) for PDB: 4AEL
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50365476(CHEMBL1957361)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50365476(CHEMBL1957361)
Affinity DataIC50:  12nMAssay Description:Inhibition of human PDE10A catalytic domain expressed in Escherichia coli BL21-Gold(DE3) by enzyme inhibition assayMore data for this Ligand-Target Pair