Found 4 Enz. Inhib. hit(s) for PDB: 4BXN TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...More data for this Ligand-Target Pair
3D Structure (crystal)TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of MT-stimulated ATPase activity of wild type Eg5 (unknown origin)More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of microtubule-stimulated ATPase activity of N-terminal His-6-tagged human wild type Eg5 (1 to 368) expressed in Escherichia coli BL21 by ...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
The Beatson Institute For Cancer Research
Curated by ChEMBL
The Beatson Institute For Cancer Research
Curated by ChEMBL
Affinity DataKd: >10nMAssay Description:Binding affinity to human wild type Eg5 at 250 uM by isothermal calorimetric analysisMore data for this Ligand-Target Pair
