Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 4MSU
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of biotin-tagged human GKRP-fluorescein-tagged human GK interaction preincubated for 20 mins followed by fluorescein-tagged human GK addit...More data for this Ligand-Target Pair
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)
Affinity DataKd:  240nMAssay Description:Binding affinity to GKRP (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)
Affinity DataEC50:  3.64E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair