Found 4 Enz. Inhib. hit(s) for PDB: 4XT2 TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Binding affinity to wild type GST-tagged HIF-2alpha PAS-B (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibition of inter...More data for this Ligand-Target Pair
3D Structure (crystal)TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity to wild type GST-tagged HIF-2alpha PAS-B S304M mutant (240 to 350) (unknown origin) expressed in Escherichia coli assessed as inhibi...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataKd: 70nMAssay Description:Binding affinity to wild type His6-Gbeta1-fused HIF-2alpha PAS-B domain (240 to 350) (unknown origin) expressed in Escherichia coli by ITC analysisMore data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1(Homo sapiens (Human))
University Of Texas Southwestern Medical Center
Curated by ChEMBL
University Of Texas Southwestern Medical Center
Curated by ChEMBL
Affinity DataKd: 63nMAssay Description:Binding affinity to wild type His6-Gbeta1-fused HIF-2alpha PAS-B domain (240 to 350) (unknown origin) expressed in Escherichia coli by ITC analysisMore data for this Ligand-Target Pair
