Found 10 Enz. Inhib. hit(s) for PDB: 4YBI 
Affinity DataIC50: 173nMAssay Description:Inhibition of BACE 1 (unknown origin) using 250 nM of Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 239nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of human BACE-1More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of IgG1 Fc-fused human recombinant BACE1 (1 to 460 residues) expressed in HEK293 cells using methylcoumarin peptide harboring Swedish muta...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human BACE1 by 7-methoxycoumarin-4-yl-acetyl-based FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of BACE1 in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta 40 or amyloid beta 42 production incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant BACE1 using MBP-C125Swe as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of BACE-1 in HEK293 cells expressing human APP751 cDNA harboring N670L671 mutation pretreated for 2 hrs followed by measuring after 2 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of human BACE1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate measured after 2 hrs by FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APPswedish mutant assessed as inhibition of amyloid beta production by ELISAMore data for this Ligand-Target Pair
