Found 3 Enz. Inhib. hit(s) for PDB: 4YLJ TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Technische Universit£T Braunschweig
Curated by ChEMBL
Technische Universit£T Braunschweig
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
3D Structure (crystal)TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Technische Universit£T Braunschweig
Curated by ChEMBL
Technische Universit£T Braunschweig
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of DYRK1A in HEK293 cells assessed as inhibition of tau phosphorylation at Thr212 by Western blotting analysisMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Technische Universit£T Braunschweig
Curated by ChEMBL
Technische Universit£T Braunschweig
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of DYRK1A in human HeLa cells assessed as reduction of SF3B1 phosphorylation by immunoblotting analysisMore data for this Ligand-Target Pair
