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Found 3 Enz. Inhib. hit(s) for PDB: 5TCC
TargetComplement factor D(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50201569(CHEMBL3924715)
Affinity DataIC50:  77nMAssay Description:Inhibition of human serum factor D-mediated complement activation in rabbit erythrocytes assessed as reduction in rabbit erythrocyte hemolysis preinc...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50201569(CHEMBL3924715)
Affinity DataIC50:  2.18E+3nMAssay Description:Competitive inhibition of human complement factor D preincubated for 1 hr followed by addition of Z-Lys-thiobenzyl ester as substrate measured over 5...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50201569(CHEMBL3924715)
Affinity DataKd:  2.21E+3nMAssay Description:Binding affinity to recombinant human C-terminal 6His-tagged/biotinylated complement factor D (26 to 253 residues) expressed in Sf9 insect cells by b...More data for this Ligand-Target Pair