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PDB code 6F90

Compile Data Set for Download or QSAR

Identical Ligands in BindingDB

Found 1 hit Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GH92 alpha-mannosidase

  (717/717 = 100%)
(Bacteroides thetaiotaomicron )
BDBM36373
PNG
((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Show SMILES OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)c2nccn12
Show InChI InChI=1S/C8H12N2O4/c11-3-4-5(12)6(13)7(14)8-9-1-2-10(4)8/h1-2,4-7,11-14H,3H2/t4-,5-,6+,7+/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
6.00E+5n/an/an/an/an/an/an/an/a



Newcastle University

Curated by ChEMBL


Assay Description
Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1032 assessed as reduction of mannose release using 4NP-mannopyranoside substrate


Nat Chem Biol 6: 125-32 (2010)


Article DOI: 10.1038/nchembio.278
BindingDB Entry DOI: 10.7270/Q2ZW1PQB
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)

Search BindingMOAD for More Affinity Data:

* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
Identities from BLAST output