Compile Data Set for Download or QSAR
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Found 12 Enz. Inhib. hit(s) with all data for entry = 50008583
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075026(Acetic acid 1,1-diacetoxy-3-oxo-1lambda*5*-ioda-2-...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075023(1-Iodyl-4-nitro-benzene | CHEMBL118424)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075025(4-Iodyl-benzoic acid | CHEMBL119805)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075030(1-tert-Butylperoxy-1H-1lambda*3*-benzo[d][1,2]iodo...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075031(1,3-Dioxo-1H-1lambda*5*-ioda-2,4-dioxa-3lambda*5*-...)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075029(3-Iodyl-benzoic acid | CHEMBL332161)
Affinity DataIC50:  8.90E+5nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075020(5-Iodyl-1H-imidazole | CHEMBL120421)
Affinity DataIC50:  1.05E+6nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075024(1-Iodyl-3-nitro-benzene | CHEMBL118998)
Affinity DataIC50:  1.14E+6nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075028(1-hydroxy-1,3-dioxobenziodoxole | 1-hydroxy-1lambd...)
Affinity DataIC50:  1.16E+6nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075021(1,4-Diiodyl-benzene | CHEMBL118312)
Affinity DataIC50:  1.41E+6nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075027(1-Iodyl-4-methyl-benzene | CHEMBL119071)
Affinity DataIC50:  1.51E+6nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50075022(CHEMBL325174 | Iodyl-benzene)
Affinity DataIC50:  2.65E+6nMAssay Description:Inhibition of protein tyrosine phosphatase 1B (PTP1B) activity in 3,6-fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed