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Found 13 Enz. Inhib. hit(s) with all data for entry = 50008610
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075302((3-ethynylphenyl)(difluoro)methylphosphonate | CHE...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075306(CHEMBL151494 | {3-[bis(methylsulfonyl)amino]-4-[(E...)
Affinity DataIC50:  5.79E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075313(CHEMBL150915 | [(4-Ethynyl-phenyl)-difluoro-methyl...)
Affinity DataIC50:  7.75E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075310(CHEMBL357094 | [3-[bis(methylsulfonyl)amino]-4-(ph...)
Affinity DataIC50:  8.87E+4nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075305(CHEMBL149279 | [Difluoro-(4-phenylethynyl-phenyl)-...)
Affinity DataIC50:  1.28E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075309(CHEMBL150420 | [Difluoro-(3-phenylethynyl-phenyl)-...)
Affinity DataIC50:  1.36E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075303(CHEMBL150349 | [Difluoro-(3-methanesulfonylamino-4...)
Affinity DataIC50:  1.67E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075311(CHEMBL150350 | [Difluoro-(3-methanesulfonylamino-4...)
Affinity DataIC50:  1.76E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075314(CHEMBL151300 | difluoro{3-[(E)-2-phenylvinyl]pheny...)
Affinity DataIC50:  3.86E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075304(CHEMBL150295 | {Difluoro-[4-((E)-styryl)-phenyl]-m...)
Affinity DataIC50:  4.50E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075307(CHEMBL150202 | [Difluoro-(4'-methoxy-biphenyl-4-yl...)
Affinity DataIC50:  4.51E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075312((Difluoro-naphthalen-2-yl-methyl)-phosphonic acid ...)
Affinity DataIC50:  7.18E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Tokyo University Of Pharmacy & Life Science

Curated by ChEMBL
LigandPNGBDBM50075308((Biphenyl-4-yl-difluoro-methyl)-phosphonic acid | ...)
Affinity DataIC50:  7.79E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed