Compile Data Set for Download or QSAR
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Found 40 Enz. Inhib. hit(s) with all data for entry = 50035039
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076005(2-[11,15-dimethoxy-3-methyl-(14R,15S)-13-oxa-3-aza...)
Affinity DataKi:  0.100nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076002(2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451002(CHEMBL2110199)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076003(3-cyclopropylmethyl-18,18-dimethyl-(15S)-13,16-dio...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076011(3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076002(2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076002(2-(3-cyclopropylmethyl-11-hydroxy-15-methoxy-13-ox...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076007(2-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacyclo[...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076010(3,17,17,18-tetramethyl-13,16-dioxa-3-azaheptacyclo...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076011(3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human mu opioid receptor in CHO cells using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076005(2-[11,15-dimethoxy-3-methyl-(14R,15S)-13-oxa-3-aza...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451004(CHEMBL2110315)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076003(3-cyclopropylmethyl-18,18-dimethyl-(15S)-13,16-dio...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076011(3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076007(2-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacyclo[...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076001(3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076003(3-cyclopropylmethyl-18,18-dimethyl-(15S)-13,16-dio...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076001(3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards human delta opioid receptor in CHO cells using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076001(3-cyclopropylmethyl-18-methyl-(15S)-13,16-dioxa-3-...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076007(2-(11,15-dimethoxy-3-methyl-13-oxa-3-azahexacyclo[...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50354578(BUPRENORPHINE | US10752592, Compound buprenorphine...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards mu opioid receptor in guinea pig brain membranes using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50354578(BUPRENORPHINE | US10752592, Compound buprenorphine...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50354578(BUPRENORPHINE | US10752592, Compound buprenorphine...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076005(2-[11,15-dimethoxy-3-methyl-(14R,15S)-13-oxa-3-aza...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity towards human kappa opioid receptor in CHO cells using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076010(3,17,17,18-tetramethyl-13,16-dioxa-3-azaheptacyclo...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451002(CHEMBL2110199)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451004(CHEMBL2110315)
Affinity DataKi:  4.40nMAssay Description:Binding affinity towards kappa opioid receptor in guinea pig brain membranes using [3H]- U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076010(3,17,17,18-tetramethyl-13,16-dioxa-3-azaheptacyclo...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451002(CHEMBL2110199)
Affinity DataKi:  4.40nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451004(CHEMBL2110315)
Affinity DataKi:  6.10nMAssay Description:Binding affinity towards delta opioid receptor in guinea pig brain membranes using [3H]- CI-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451004(CHEMBL2110315)
Affinity DataEC50:  28nMAssay Description:Activity was evaluated in human delta opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataEC50:  5nMAssay Description:Activity was evaluated in human delta opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataEC50:  1.20nMAssay Description:Activity was evaluated in human delta opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50354578(BUPRENORPHINE | US10752592, Compound buprenorphine...)
Affinity DataEC50:  2.30nMAssay Description:Activity was evaluated in human mu opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451004(CHEMBL2110315)
Affinity DataEC50:  1.90nMAssay Description:Activity was evaluated in human mu opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50451004(CHEMBL2110315)
Affinity DataEC50:  21nMAssay Description:Activity was evaluated in human kappa opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50076009(16-[1-hydroxy-1,2,2-trimethyl-(1R)-propyl]-15-meth...)
Affinity DataEC50:  2.40nMAssay Description:Activity was evaluated in human kappa opioid receptors transfected with CHO cells by [35S]GTP-gamma-S, assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed