Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50008684
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076052((S)-3-[4-(5-Amino-pentyloxy)-benzoylamino]-2-benze...)
Affinity DataIC50:  13nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076058((S)-2-Benzenesulfonylamino-3-(4-piperazin-1-yl-ben...)
Affinity DataIC50:  17nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076055((S)-3-[4-(4-Amino-butoxy)-benzoylamino]-2-benzenes...)
Affinity DataIC50:  23nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076060((S)-2-Benzenesulfonylamino-3-(4-piperazin-1-ylmeth...)
Affinity DataIC50:  34nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076065((S)-3-[4-(3-Amino-propoxy)-benzoylamino]-2-benzene...)
Affinity DataIC50:  55nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076064((S)-3-[4-(2-Amino-ethoxy)-benzoylamino]-2-benzenes...)
Affinity DataIC50:  110nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076053((S)-2-Benzenesulfonylamino-3-[4-(2-piperidin-2-yl-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076061((S)-3-[4-(3-Amino-propyl)-benzoylamino]-2-benzenes...)
Affinity DataIC50:  270nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076056((R)-3-[2-(7-Amino-heptanoylamino)-acetylamino]-2-b...)
Affinity DataIC50:  380nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076054((R)-3-[2-(6-Amino-hexanoylamino)-acetylamino]-2-be...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076059((S)-3-[4-(2-Amino-ethyl)-benzoylamino]-2-benzenesu...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076051((S)-3-[3-(2-Amino-ethoxy)-benzoylamino]-2-benzenes...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076062((R)-3-[2-(5-Amino-pentanoylamino)-acetylamino]-2-b...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076063((R)-3-[2-(4-Amino-butyrylamino)-acetylamino]-2-ben...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076057(3-(4-Piperazin-1-yl-benzoylamino)-propionic acid |...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of glycoprotein IIb/III integrin mediated fibrinogen binding to activated plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed