Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50008746
LigandPNGBDBM50067563((S)-2-{[2'-Methyl-5-(pyridin-3-yloxymethyl)-biphen...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50067584((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076811(CHEMBL10877 | Lithium; (S)-2-({5-[5-(4-chloro-phen...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076809(CHEMBL417606 | Lithium; (S)-2-({5-[5-(4-formyl-phe...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076798(CHEMBL273697 | Lithium; (S)-2-({5-[5-(4-fluoro-phe...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076802(CHEMBL10912 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...)
Affinity DataIC50:  2.40nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076795(CHEMBL11210 | Lithium; (S)-2-({5-[5-(4-dimethylami...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076794(CHEMBL276602 | Lithium; (S)-2-({5-[5-(4-isopropyl-...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076791(CHEMBL10990 | Lithium; (S)-4-methylsulfanyl-2-{[2'...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076810(CHEMBL428001 | Lithium; (S)-4-methylsulfanyl-2-({2...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076799((S)-2-{[5-(5-Bromo-furan-2-ylmethoxymethyl)-2'-met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076792(CHEMBL10812 | Lithium; (S)-2-({5-[5-(4-chloro-3-fl...)
Affinity DataIC50:  4.90nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076801(CHEMBL430096 | Lithium; (S)-2-({2'-methyl-5-[5-(3-...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076797(CHEMBL10955 | Lithium; (S)-2-{[2'-methyl-5-(5-phen...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076793(CHEMBL11003 | Lithium; (S)-2-({2'-methyl-5-[5-(4-m...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076803(CHEMBL10970 | Lithium; (S)-2-({5-[5-(2-fluoro-phen...)
Affinity DataIC50:  6.30nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076790(CHEMBL10902 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...)
Affinity DataIC50:  6.5nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076800(CHEMBL430307 | Lithium; (S)-2-({5-[5-(4-acetyl-phe...)
Affinity DataIC50:  6.60nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076788(CHEMBL11195 | Lithium; (S)-2-({5-[5-(3-fluoro-phen...)
Affinity DataIC50:  7.60nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076806(CHEMBL273265 | Lithium; (S)-2-({5-[5-(4-methoxy-ph...)
Affinity DataIC50:  8.40nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076804(CHEMBL273507 | Lithium; (S)-4-methylsulfanyl-2-({2...)
Affinity DataIC50:  8.80nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076789(CHEMBL274672 | Lithium; (S)-4-methylsulfanyl-2-({2...)
Affinity DataIC50:  9.90nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076807(CHEMBL273721 | Lithium; (S)-2-({5-[5-(3-methoxy-ph...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076808(CHEMBL10762 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076813(CHEMBL10687 | Lithium; (S)-2-({5-[5-(2-methoxy-phe...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076812((S)-2-[(5-{[(Furan-2-ylmethyl)-amino]-methyl}-biph...)
Affinity DataIC50:  560nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076805((S)-4-Methylsulfanyl-2-[(5-phenoxymethyl-biphenyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound was evaluated against farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076793(CHEMBL11003 | Lithium; (S)-2-({2'-methyl-5-[5-(4-m...)
Affinity DataEC50:  10nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076802(CHEMBL10912 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...)
Affinity DataEC50: >0.300nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076806(CHEMBL273265 | Lithium; (S)-2-({5-[5-(4-methoxy-ph...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076801(CHEMBL430096 | Lithium; (S)-2-({2'-methyl-5-[5-(3-...)
Affinity DataEC50:  10nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076810(CHEMBL428001 | Lithium; (S)-4-methylsulfanyl-2-({2...)
Affinity DataEC50:  1.20nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076808(CHEMBL10762 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...)
Affinity DataEC50: >0.300nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076807(CHEMBL273721 | Lithium; (S)-2-({5-[5-(3-methoxy-ph...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076794(CHEMBL276602 | Lithium; (S)-2-({5-[5-(4-isopropyl-...)
Affinity DataEC50:  0.780nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076811(CHEMBL10877 | Lithium; (S)-2-({5-[5-(4-chloro-phen...)
Affinity DataEC50:  0.100nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076797(CHEMBL10955 | Lithium; (S)-2-{[2'-methyl-5-(5-phen...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076791(CHEMBL10990 | Lithium; (S)-4-methylsulfanyl-2-{[2'...)
Affinity DataEC50:  1.80nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076800(CHEMBL430307 | Lithium; (S)-2-({5-[5-(4-acetyl-phe...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076803(CHEMBL10970 | Lithium; (S)-2-({5-[5-(2-fluoro-phen...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076795(CHEMBL11210 | Lithium; (S)-2-({5-[5-(4-dimethylami...)
Affinity DataEC50:  0.900nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076788(CHEMBL11195 | Lithium; (S)-2-({5-[5-(3-fluoro-phen...)
Affinity DataEC50:  10nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076809(CHEMBL417606 | Lithium; (S)-2-({5-[5-(4-formyl-phe...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076790(CHEMBL10902 | Lithium; (S)-2-{[2'-methyl-5-(5-pyri...)
Affinity DataEC50:  0.300nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076813(CHEMBL10687 | Lithium; (S)-2-({5-[5-(2-methoxy-phe...)
Affinity DataEC50: >1nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076798(CHEMBL273697 | Lithium; (S)-2-({5-[5-(4-fluoro-phe...)
Affinity DataEC50:  1.5nMAssay Description:EC50 is measured as inhibition of ras processing in a whole cell assay for farnesyltransferase (FTase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed