Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50008757
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50049024(4-[6-(4-Fluoro-phenyl)-spiro[2.4]hept-5-en-5-yl]-b...)
Affinity DataIC50:  3nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076888(4-[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-benz...)
Affinity DataIC50:  5nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076880(4-[2-(3,5-Dichloro-phenoxymethyl)-4-(4-fluoro-phen...)
Affinity DataIC50:  9nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076883(4-[2-Benzylamino-4-(3-fluoro-4-methoxy-phenyl)-thi...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076884(4-[2-(2-Chloro-phenyl)-4-(4-fluoro-phenyl)-thiazol...)
Affinity DataIC50:  13nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076882(4-[5-(4-Chloro-phenyl)-2-methyl-thiazol-4-yl]-benz...)
Affinity DataIC50:  18nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076885(4-[5-(4-Bromo-phenyl)-2-methyl-thiazol-4-yl]-benze...)
Affinity DataIC50:  24nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076887(4-[4-(3-Fluoro-4-methoxy-phenyl)-2-methyl-thiazol-...)
Affinity DataIC50:  28nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076886(4-(2-Methyl-5-phenyl-thiazol-4-yl)-benzenesulfonam...)
Affinity DataIC50:  29nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076881(4-(2-Methyl-4-phenyl-thiazol-5-yl)-benzenesulfonam...)
Affinity DataIC50:  38nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  40nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076883(4-[2-Benzylamino-4-(3-fluoro-4-methoxy-phenyl)-thi...)
Affinity DataIC50:  59nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076884(4-[2-(2-Chloro-phenyl)-4-(4-fluoro-phenyl)-thiazol...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076880(4-[2-(3,5-Dichloro-phenoxymethyl)-4-(4-fluoro-phen...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50049024(4-[6-(4-Fluoro-phenyl)-spiro[2.4]hept-5-en-5-yl]-b...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076888(4-[4-(4-Chloro-phenyl)-2-methyl-thiazol-5-yl]-benz...)
Affinity DataIC50:  1.84E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076879(4-[2-(2-Chloro-phenyl)-4-(3-fluoro-4-methoxy-pheny...)
Affinity DataIC50:  2.48E+3nMAssay Description:Compound was evaluated in vitro for its inhibitory activity against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076887(4-[4-(3-Fluoro-4-methoxy-phenyl)-2-methyl-thiazol-...)
Affinity DataIC50:  4.18E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076881(4-(2-Methyl-4-phenyl-thiazol-5-yl)-benzenesulfonam...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076882(4-[5-(4-Chloro-phenyl)-2-methyl-thiazol-4-yl]-benz...)
Affinity DataIC50:  3.56E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076886(4-(2-Methyl-5-phenyl-thiazol-4-yl)-benzenesulfonam...)
Affinity DataIC50:  7.25E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076879(4-[2-(2-Chloro-phenyl)-4-(3-fluoro-4-methoxy-pheny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
G.D. Searle-Monsanto

Curated by ChEMBL
LigandPNGBDBM50076885(4-[5-(4-Bromo-phenyl)-2-methyl-thiazol-4-yl]-benze...)
Affinity DataIC50:  1.15E+5nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed