Compile Data Set for Download or QSAR
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Found 15 Enz. Inhib. hit(s) with all data for entry = 50008770
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)
Affinity DataIC50:  92nMAssay Description:Inhibitory activity against cloned human Beta-3 adrenergic receptor in the presence of [125I]-iodocyanopindolol expressed in CHO cells by receptor bi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076959(CHEMBL22318 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against cloned human Beta-2 adrenergic receptor in the presence of [125I]-iodocyanopindolol in CHO cells by receptor binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076959(CHEMBL22318 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against cloned human Beta-1 adrenergic receptor in the presence of [125I]-iodocyanopindolol in CHO cells by receptor binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)
Affinity DataIC50:  1.60E+3nMAssay Description:Agonistic activity against the cloned human Beta-3 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076961(4-(4-Hexyl-5-oxo-4,5-dihydro-tetrazol-1-yl)-N-{4-[...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity against cloned human Beta-2 adrenergic receptor in the presence of [125I]-iodocyanopindolol in CHO cells by receptor binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against cloned human Beta-1 adrenergic receptor in the presence of [125I]-iodocyanopindolol expressed in CHO cells by receptor bi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076961(4-(4-Hexyl-5-oxo-4,5-dihydro-tetrazol-1-yl)-N-{4-[...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against cloned human Beta-1 adrenergic receptor in the presence of [125I]-iodocyanopindolol in CHO cells by receptor binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonistic activity against the cloned human Beta-1 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076959(CHEMBL22318 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  370nMAssay Description:Inhibitory activity against cloned human Beta-2 adrenergic receptor in the presence of [125I]-iodocyanopindolol in CHO cells by receptor binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075906(4-[3-(3-Cyclopentyl-propyl)-2-oxo-imidazolidin-1-y...)
Affinity DataEC50:  5.70nMAssay Description:Agonistic activity against the cloned human Beta-3 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076961(4-(4-Hexyl-5-oxo-4,5-dihydro-tetrazol-1-yl)-N-{4-[...)
Affinity DataEC50:  30nMAssay Description:Agonistic activity against the cloned human Beta-3 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)
Affinity DataEC50:  13nMAssay Description:Agonistic activity against the cloned human Beta-1 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076959(CHEMBL22318 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  6.30nMAssay Description:Agonistic activity against the cloned human Beta-3 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonistic activity against the cloned human Beta-2 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075889(4-(3-Hexyl-2-oxo-2,3-dihydro-imidazol-1-yl)-N-{4-[...)
Affinity DataEC50:  14nMAssay Description:Agonistic activity against the cloned human Beta-3 adrenergic receptor was measured by its by its ability to stimulate adenylyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed