Compile Data Set for Download or QSAR
maximum 50k data
Found 49 Enz. Inhib. hit(s) with all data for entry = 50008918
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078544(3-[(3R,3aS,8aS)-1-Benzenesulfonyl-3-(4-carbamimido...)
Affinity DataIC50:  16nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078554((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  16nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078554((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078553((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078544(3-[(3R,3aS,8aS)-1-Benzenesulfonyl-3-(4-carbamimido...)
Affinity DataIC50:  66nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078544(3-[(3R,3aS,8aS)-1-Benzenesulfonyl-3-(4-carbamimido...)
Affinity DataIC50:  74nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078554((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  120nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078552((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  130nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078556(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078557((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  620nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078557((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  660nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078549((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078551(CHEMBL46365 | [(3R,3aS,8aS)-3-(4-Carbamimidoyl-but...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078553((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078553((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078552((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078546((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078551(CHEMBL46365 | [(3R,3aS,8aS)-3-(4-Carbamimidoyl-but...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078557((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078552((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078560((1S,2R,4aR,6aS,6bS,7R,9aR,10aS)-2-Acetoxy-1,4a,6a,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078547(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078548(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078549((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078549((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-6-(3-diethy...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078556(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078548(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078558(5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078556(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078555((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078545(Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078558(5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078545(Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078555((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078555((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078551(CHEMBL46365 | [(3R,3aS,8aS)-3-(4-Carbamimidoyl-but...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078548(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078545(Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078550(CHEMBL295211 | [(3R,3aS,8aS)-3-(4-Carbamimidoyl-bu...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078547(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078547(3-[(3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-2-oxo-1-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078558(5-[(3R,3aS,8aS)-2-Oxo-1-(5-phenyl-pentyl)-1,2,3,3a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078546((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078546((3R,3aS,8aS)-3-(4-Carbamimidoyl-butyl)-5-(3-diethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078550(CHEMBL295211 | [(3R,3aS,8aS)-3-(4-Carbamimidoyl-bu...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078559(5-((3R,3aS,8aS)-2-Oxo-1,2,3,3a,8,8a-hexahydro-inde...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078559(5-((3R,3aS,8aS)-2-Oxo-1,2,3,3a,8,8a-hexahydro-inde...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078550(CHEMBL295211 | [(3R,3aS,8aS)-3-(4-Carbamimidoyl-bu...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development

Curated by ChEMBL
LigandPNGBDBM50078559(5-((3R,3aS,8aS)-2-Oxo-1,2,3,3a,8,8a-hexahydro-inde...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed