Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50034999
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078569((S)-4-(Biphenyl-4-ylmethylsulfanyl)-N-hydroxy-2-[i...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target72 kDa type IV collagenase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  7nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50:  8nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  14nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  15nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50:  20nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078569((S)-4-(Biphenyl-4-ylmethylsulfanyl)-N-hydroxy-2-[i...)
Affinity DataIC50:  20nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50:  29nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078569((S)-4-(Biphenyl-4-ylmethylsulfanyl)-N-hydroxy-2-[i...)
Affinity DataIC50:  30nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  37nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  45nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50:  49nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  53nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50:  90nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  96nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  96nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50:  104nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50:  156nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  384nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed