Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50009009
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079431(3-(3,4-Dimethoxy-phenoxy)-2-(4,6-dimethyl-pyrimidi...)
Affinity DataKi:  0.480nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079426(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  1.38nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079432(4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079430(3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2...)
Affinity DataKi:  1.92nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079439(2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-m...)
Affinity DataKi:  1.95nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079438(3-(3,4-Dimethoxy-benzyloxy)-2-(4,6-dimethyl-pyrimi...)
Affinity DataKi:  2nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079424((S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dim...)
Affinity DataKi:  2.15nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079429(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6...)
Affinity DataKi:  2.37nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079435(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-...)
Affinity DataKi:  3.13nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079426(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  3.21nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079423(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy...)
Affinity DataKi:  3.48nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079417(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethy...)
Affinity DataKi:  3.49nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079424((S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dim...)
Affinity DataKi:  4.75nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079427(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy...)
Affinity DataKi:  6.03nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079417(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethy...)
Affinity DataKi:  7.15nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079429(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6...)
Affinity DataKi:  14.7nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079423(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy...)
Affinity DataKi:  16.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079428(3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyr...)
Affinity DataKi:  19.8nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079422(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  20nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079421(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  23nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079439(2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-m...)
Affinity DataKi:  23.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079430(3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2...)
Affinity DataKi:  24nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079427(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy...)
Affinity DataKi:  24.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079425(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-phenethyloxy-...)
Affinity DataKi:  25nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079435(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079419(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  32nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079436(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  32.5nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079416(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-eth...)
Affinity DataKi:  39.3nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079416(3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-eth...)
Affinity DataKi:  40nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079422(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  48nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079436(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  55nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079431(3-(3,4-Dimethoxy-phenoxy)-2-(4,6-dimethyl-pyrimidi...)
Affinity DataKi:  60nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079438(3-(3,4-Dimethoxy-benzyloxy)-2-(4,6-dimethyl-pyrimi...)
Affinity DataKi:  63nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079420(2-(4-Methoxy-5,7-dihydro-furo[3,4-d]pyrimidin-2-yl...)
Affinity DataKi:  71.2nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079428(3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyr...)
Affinity DataKi:  94.1nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079420(2-(4-Methoxy-5,7-dihydro-furo[3,4-d]pyrimidin-2-yl...)
Affinity DataKi:  105nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079432(4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)...)
Affinity DataKi:  115nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079418(3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phen...)
Affinity DataKi:  130nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079433(3,3-Bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyr...)
Affinity DataKi:  155nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079433(3,3-Bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyr...)
Affinity DataKi:  160nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079421(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  170nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079434(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-bis-(4-ethy...)
Affinity DataKi:  195nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079437(3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phen...)
Affinity DataKi:  215nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079418(3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phen...)
Affinity DataKi:  230nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079425(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-phenethyloxy-...)
Affinity DataKi:  230nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079434(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-bis-(4-ethy...)
Affinity DataKi:  250nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079437(3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phen...)
Affinity DataKi:  290nMAssay Description:Inhibition of [125I]-ET-1 (ETA assay) binding to human cloned Endothelin A receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Basf

Curated by ChEMBL
LigandPNGBDBM50079419(2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-...)
Affinity DataKi:  320nMAssay Description:Inhibition of [125I]-ET-3 (ETB assay) binding to human cloned Endothelin B receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed