Compile Data Set for Download or QSAR
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Found 22 Enz. Inhib. hit(s) with all data for entry = 50009061
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079775(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079784(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079783(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataIC50:  4.20nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079776(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079782(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataIC50:  5.90nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079778(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079779(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079780(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  7.90nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079781(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079774(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein phosphatase 3 catalytic subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079777((E)-(1R,9S,12S,13R,14R,21S,23S,24R,25S,27R)-17-All...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against Calcineurin (CaN phosphatase)More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079775(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataEC50:  21nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079782(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataEC50:  45nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079780(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  7.5nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079774(12-(2-{4-[2-(3,5-Dimethyl-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  9nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079776(17-Ethyl-1,14-dihydroxy-12-(2-{4-[2-hydroxy-2-(3-t...)
Affinity DataEC50:  45nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079783(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataEC50:  12nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079784(12-{2-[4-(2-Benzo[b]thiophen-2-yl-2-hydroxy-ethoxy...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079777((E)-(1R,9S,12S,13R,14R,21S,23S,24R,25S,27R)-17-All...)
Affinity DataEC50:  0.900nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079778(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  7.5nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079779(17-Ethyl-1,14-dihydroxy-12-{2-[4-(2-hydroxy-2-naph...)
Affinity DataEC50:  18nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50079781(12-(2-{4-[2-(3,4-Difluoro-phenyl)-2-hydroxy-ethoxy...)
Affinity DataEC50:  14nMAssay Description:Effective concentration against FK506 binding protein 12 using [3H]-dihydro FK-506More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed