Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50035015
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080949((S)-2-[4-(3-Phenyl-propoxy)-benzylamino]-propionam...)
Affinity DataIC50:  19nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50078694((S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propion...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080940((S)-2-[4-(3-Fluoro-benzylamino)-benzylamino]-propi...)
Affinity DataIC50:  34nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080941((R)-2-[4-(3-Fluoro-benzylamino)-benzylamino]-propi...)
Affinity DataIC50:  280nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080948((R)-2-[4-(3-Phenyl-propoxy)-benzylamino]-propionam...)
Affinity DataIC50:  280nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080950((R)-2-(4-(3-fluorobenzyloxy)benzylamino)propanamid...)
Affinity DataIC50:  280nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080943((S)-2-[4-(4-Phenyl-butoxy)-benzylamino]-propionami...)
Affinity DataIC50:  550nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080945((S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-3-hydro...)
Affinity DataIC50:  588nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080943((S)-2-[4-(4-Phenyl-butoxy)-benzylamino]-propionami...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080942((S)-2-[4-(5-Phenyl-pentyloxy)-benzylamino]-propion...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080947((R)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-3-hydro...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080948((R)-2-[4-(3-Phenyl-propoxy)-benzylamino]-propionam...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50078694((S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propion...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080950((R)-2-(4-(3-fluorobenzyloxy)benzylamino)propanamid...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50031299(6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080942((S)-2-[4-(5-Phenyl-pentyloxy)-benzylamino]-propion...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080939((S)-2-(4-Methoxy-benzylamino)-propionamide | CHEMB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]pentazocine binding to Opioid receptor sigma 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080941((R)-2-[4-(3-Fluoro-benzylamino)-benzylamino]-propi...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080949((S)-2-[4-(3-Phenyl-propoxy)-benzylamino]-propionam...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080940((S)-2-[4-(3-Fluoro-benzylamino)-benzylamino]-propi...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080947((R)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-3-hydro...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080945((S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-3-hydro...)
Affinity DataIC50:  2.63E+4nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50031299(6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080939((S)-2-(4-Methoxy-benzylamino)-propionamide | CHEMB...)
Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50217151(CHEMBL419673)
Affinity DataIC50:  1.51E+5nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50031299(6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamin...)
Affinity DataIC50:  1.86E+5nMAssay Description:Inhibition of [3H]batrachotoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080940((S)-2-[4-(3-Fluoro-benzylamino)-benzylamino]-propi...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080949((S)-2-[4-(3-Phenyl-propoxy)-benzylamino]-propionam...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080947((R)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-3-hydro...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50217151(CHEMBL419673)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080945((S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-3-hydro...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080948((R)-2-[4-(3-Phenyl-propoxy)-benzylamino]-propionam...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080939((S)-2-(4-Methoxy-benzylamino)-propionamide | CHEMB...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50078694((S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propion...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080942((S)-2-[4-(5-Phenyl-pentyloxy)-benzylamino]-propion...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080950((R)-2-(4-(3-fluorobenzyloxy)benzylamino)propanamid...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080943((S)-2-[4-(4-Phenyl-butoxy)-benzylamino]-propionami...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Pharmacia & Upjohn

Curated by ChEMBL
LigandPNGBDBM50080941((R)-2-[4-(3-Fluoro-benzylamino)-benzylamino]-propi...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]saxitoxin binding to rat brain sodium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed