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Found 41 Enz. Inhib. hit(s) with all data for entry = 50009617
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085629(2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-(1-m...)
Affinity DataKi:  41nMAssay Description:The compound was tested for inhibition of Lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085626(2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-pyri...)
Affinity DataIC50:  54nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085655(2-[8-(4-Chloro-phenyl)-8-oxo-octyloxy]-5-pyridin-3...)
Affinity DataIC50:  64nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085629(2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-(1-m...)
Affinity DataIC50:  72nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085616(2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-pyri...)
Affinity DataIC50:  110nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085634(2-[8-(4-Chloro-phenyl)-octylsulfanyl]-5-pyridin-3-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085620(2-[7-(4-Chloro-phenoxy)-heptylsulfanyl]-5-pyridin-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085622(5-(1-Methyl-2-oxo-1,2-dihydro-pyridin-4-ylmethyl)-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085628(2-[7-(4-Chloro-phenylsulfanyl)-heptylsulfanyl]-5-p...)
Affinity DataIC50:  250nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085625(2-(8-Phenyl-octylsulfanyl)-5-pyridin-3-ylmethyl-1H...)
Affinity DataIC50:  330nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085640(2-(9-Phenyl-nonylsulfanyl)-5-pyridin-3-ylmethyl-1H...)
Affinity DataIC50:  430nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085652(2-(8-Phenyl-octylsulfanyl)-5-pyridin-4-ylmethyl-1H...)
Affinity DataIC50:  630nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085648(2-[8-(4-Chloro-phenyl)-8-oxo-octylsulfanyl]-5-pyra...)
Affinity DataIC50:  640nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085651(2-[9-(4-Chloro-phenyl)-9-oxo-nonylsulfanyl]-5-pyri...)
Affinity DataIC50:  650nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085633(5-(1-Butyl-2-oxo-1,2-dihydro-pyridin-4-ylmethyl)-2...)
Affinity DataIC50:  780nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085624(5-(6-Methyl-pyridin-3-ylmethyl)-2-(8-phenyl-octyls...)
Affinity DataIC50:  780nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085631(2-[8-(3-Chloro-phenyl)-octylsulfanyl]-5-pyridin-3-...)
Affinity DataIC50:  850nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085654(2-(4-Fluoro-benzylsulfanyl)-5-pyrimidin-5-ylmethyl...)
Affinity DataIC50:  850nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085643(5-(6-Methyl-pyridin-3-ylmethyl)-2-(9-phenyl-nonyls...)
Affinity DataIC50:  990nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085641(5-(2-Oxo-1,2-dihydro-pyridin-4-ylmethyl)-2-(8-phen...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085645(5-(2-Methoxy-pyridin-4-ylmethyl)-2-(8-phenyl-octyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085623(5-(6-Methyl-pyridin-3-ylmethyl)-2-(7-phenyl-heptyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085630(2-Benzylsulfanyl-5-pyridin-3-ylmethyl-1H-pyrimidin...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085627(2-(7-Phenyl-heptylsulfanyl)-5-pyridin-3-ylmethyl-1...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085649(2-Benzylsulfanyl-5-pyrimidin-5-ylmethyl-1H-pyrimid...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085650(2-[8-(4-Methoxy-phenyl)-octylsulfanyl]-5-(6-methyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085647(5-(6-Methyl-pyridin-3-ylmethyl)-2-(6-phenyl-hexyls...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085621(2-[6-(4-Chloro-benzyloxy)-hexylsulfanyl]-5-(6-meth...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085639(2-(8-Oxo-8-thiophen-2-yl-octylsulfanyl)-5-pyridin-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085617(2-Benzylsulfanyl-5-(6-methyl-pyridin-3-ylmethyl)-1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085619(2-(6-Phenyl-hexylsulfanyl)-5-pyridin-3-ylmethyl-1H...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085646(2-[8-(4-Acetyl-phenyl)-octylsulfanyl]-5-pyridin-3-...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085635(5-(4,6-Dimethyl-pyridin-3-ylmethyl)-2-(8-phenyl-oc...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085637(2-Benzylsulfanyl-5-pyridin-4-ylmethyl-1H-pyrimidin...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085638(2-(4-Chloro-benzylsulfanyl)-5-pyridin-3-ylmethyl-1...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085636(5-(6-Methyl-pyridin-3-ylmethyl)-2-phenethylsulfany...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085632(5-(6-Methyl-pyridin-3-ylmethyl)-2-(4-phenyl-butoxy...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085644(2-[7-(4-Chloro-benzenesulfonyl)-heptylsulfanyl]-5-...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085642(5-(6-Methyl-pyridin-3-ylmethyl)-2-(5-phenyl-pentyl...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085653(2-[7-(4-Chloro-benzenesulfinyl)-heptylsulfanyl]-5-...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50085618(5-(6-Methyl-pyridin-3-ylmethyl)-2-(4-phenyl-butyls...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of lipoprotein-associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed