Compile Data Set for Download or QSAR
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Found 9 Enz. Inhib. hit(s) with all data for entry = 50048498
TargetProthrombin(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218582(CHEMBL123993)
Affinity DataIC50:  54.6nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218582(CHEMBL123993)
Affinity DataIC50:  272nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218582(CHEMBL123993)
Affinity DataIC50:  409nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  870nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218585(CHEMBL3085289)
Affinity DataIC50:  916nMAssay Description:Inhibition of alpha4-beta1 VCAM binding in Jurkat cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218585(CHEMBL3085289)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of alphaL-beta2 mediated cell adhesionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218585(CHEMBL3085289)
Affinity DataIC50:  1.53E+4nMAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed