BindingDB logo
myBDB logout

PubMed code 10915040

Compile data set for download or QSAR
Found 84 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085910
PNG
((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)
Show SMILES O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085911
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1cccc(Cl)c1
Show InChI InChI=1S/C22H33ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h5-7,12,16,18-21,24-26H,1-4,8-11,13-14H2,(H,27,28)/t16-,18-,19-,20+,21-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50035622
PNG
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.5n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.60n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.60n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=90%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090133
PNG
((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)
Show SMILES O[C@@H](CCc1cccc(c1)C(F)(F)F)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090136
PNG
((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)
Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-20,23-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,18+,19-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090143
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(F)c1
Show InChI InChI=1S/C23H35FO5/c24-17-7-5-6-16(14-17)10-11-18(25)12-13-20-19(21(26)15-22(20)27)8-3-1-2-4-9-23(28)29/h5-7,14,18-22,25-27H,1-4,8-13,15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 42n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090131
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1F
Show InChI InChI=1S/C23H35FO5/c24-20-9-6-5-7-16(20)11-12-17(25)13-14-19-18(21(26)15-22(19)27)8-3-1-2-4-10-23(28)29/h5-7,9,17-19,21-22,25-27H,1-4,8,10-15H2,(H,28,29)/t17-,18+,19+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 76n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085917
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1
Show InChI InChI=1S/C23H36O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h3-5,8-9,18-22,24-26H,1-2,6-7,10-16H2,(H,27,28)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 82n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090132
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Cyano-phenyl)-3-hydro...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C#N
Show InChI InChI=1S/C24H35NO5/c25-16-18-7-5-6-17(14-18)10-11-19(26)12-13-21-20(22(27)15-23(21)28)8-3-1-2-4-9-24(29)30/h5-7,14,19-23,26-28H,1-4,8-13,15H2,(H,29,30)/t19-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090135
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(4-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccc(F)cc1
Show InChI InChI=1S/C23H35FO5/c24-17-10-7-16(8-11-17)9-12-18(25)13-14-20-19(21(26)15-22(20)27)5-3-1-2-4-6-23(28)29/h7-8,10-11,18-22,25-27H,1-6,9,12-15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090139
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1ccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)cc1
Show InChI InChI=1S/C24H38O6/c1-30-19-13-9-17(10-14-19)8-11-18(25)12-15-21-20(22(26)16-23(21)27)6-4-2-3-5-7-24(28)29/h9-10,13-14,18,20-23,25-27H,2-8,11-12,15-16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085914
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)
Show SMILES CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C20H38O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-19,21-23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,18-,19+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 522n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090130
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Ethyl-phenyl)-3-hydro...)
Show SMILES CCc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C25H40O5/c1-2-18-8-7-9-19(16-18)12-13-20(26)14-15-22-21(23(27)17-24(22)28)10-5-3-4-6-11-25(29)30/h7-9,16,20-24,26-28H,2-6,10-15,17H2,1H3,(H,29,30)/t20-,21+,22+,23-,24+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 540n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090142
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES Cc1ccccc1CC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C24H38O5/c1-17-8-6-7-9-18(17)12-13-19(25)14-15-21-20(22(26)16-23(21)27)10-4-2-3-5-11-24(28)29/h6-9,19-23,25-27H,2-5,10-16H2,1H3,(H,28,29)/t19-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 630n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090137
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)
Show SMILES CCCCC(C)(C)[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C22H42O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h16-20,23-25H,4-15H2,1-3H3,(H,26,27)/t16-,17-,18+,19-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50085917
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1
Show InChI InChI=1S/C23H36O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h3-5,8-9,18-22,24-26H,1-2,6-7,10-16H2,(H,27,28)/t18-,19+,20+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090138
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C24H38O6/c1-30-19-8-6-7-17(15-19)11-12-18(25)13-14-21-20(22(26)16-23(21)27)9-4-2-3-5-10-24(28)29/h6-8,15,18,20-23,25-27H,2-5,9-14,16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.62E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090144
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)20-9-6-5-7-16(20)11-12-17(28)13-14-19-18(21(29)15-22(19)30)8-3-1-2-4-10-23(31)32/h5-7,9,17-19,21-22,28-30H,1-4,8,10-15H2,(H,31,32)/t17-,18+,19+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.14E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090131
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1F
Show InChI InChI=1S/C23H35FO5/c24-20-9-6-5-7-16(20)11-12-17(25)13-14-19-18(21(26)15-22(19)27)8-3-1-2-4-10-23(28)29/h5-7,9,17-19,21-22,25-27H,1-4,8,10-15H2,(H,28,29)/t17-,18+,19+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090135
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(4-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccc(F)cc1
Show InChI InChI=1S/C23H35FO5/c24-17-10-7-16(8-11-17)9-12-18(25)13-14-20-19(21(26)15-22(20)27)5-3-1-2-4-6-23(28)29/h7-8,10-11,18-22,25-27H,1-6,9,12-15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.45E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090145
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-10-7-16(8-11-17)9-12-18(28)13-14-20-19(21(29)15-22(20)30)5-3-1-2-4-6-23(31)32/h7-8,10-11,18-22,28-30H,1-6,9,12-15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.63E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090143
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(F)c1
Show InChI InChI=1S/C23H35FO5/c24-17-7-5-6-16(14-17)10-11-18(25)12-13-20-19(21(26)15-22(20)27)8-3-1-2-4-9-23(28)29/h5-7,14,18-22,25-27H,1-4,8-13,15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.70E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090134
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES Cc1ccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)cc1
Show InChI InChI=1S/C24H38O5/c1-17-8-10-18(11-9-17)12-13-19(25)14-15-21-20(22(26)16-23(21)27)6-4-2-3-5-7-24(28)29/h8-11,19-23,25-27H,2-7,12-16H2,1H3,(H,28,29)/t19-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090141
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1ccccc1CC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C24H38O6/c1-30-23-10-7-6-8-17(23)12-13-18(25)14-15-20-19(21(26)16-22(20)27)9-4-2-3-5-11-24(28)29/h6-8,10,18-22,25-27H,2-5,9,11-16H2,1H3,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.89E+3n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF-2 from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090132
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Cyano-phenyl)-3-hydro...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C#N
Show InChI InChI=1S/C24H35NO5/c25-16-18-7-5-6-17(14-18)10-11-19(26)12-13-21-20(22(27)15-23(21)28)8-3-1-2-4-9-24(29)30/h5-7,14,19-23,26-28H,1-4,8-13,15H2,(H,29,30)/t19-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090135
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(4-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccc(F)cc1
Show InChI InChI=1S/C23H35FO5/c24-17-10-7-16(8-11-17)9-12-18(25)13-14-20-19(21(26)15-22(20)27)5-3-1-2-4-6-23(28)29/h7-8,10-11,18-22,25-27H,1-6,9,12-15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090130
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Ethyl-phenyl)-3-hydro...)
Show SMILES CCc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C25H40O5/c1-2-18-8-7-9-19(16-18)12-13-20(26)14-15-22-21(23(27)17-24(22)28)10-5-3-4-6-11-25(29)30/h7-9,16,20-24,26-28H,2-6,10-15,17H2,1H3,(H,29,30)/t20-,21+,22+,23-,24+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090139
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1ccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)cc1
Show InChI InChI=1S/C24H38O6/c1-30-19-13-9-17(10-14-19)8-11-18(25)12-15-21-20(22(26)16-23(21)27)6-4-2-3-5-7-24(28)29/h9-10,13-14,18,20-23,25-27H,2-8,11-12,15-16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090142
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES Cc1ccccc1CC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C24H38O5/c1-17-8-6-7-9-18(17)12-13-19(25)14-15-21-20(22(26)16-23(21)27)10-4-2-3-5-11-24(28)29/h6-9,19-23,25-27H,2-5,10-16H2,1H3,(H,28,29)/t19-,20+,21+,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090135
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(4-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccc(F)cc1
Show InChI InChI=1S/C23H35FO5/c24-17-10-7-16(8-11-17)9-12-18(25)13-14-20-19(21(26)15-22(20)27)5-3-1-2-4-6-23(28)29/h7-8,10-11,18-22,25-27H,1-6,9,12-15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090131
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1F
Show InChI InChI=1S/C23H35FO5/c24-20-9-6-5-7-16(20)11-12-17(25)13-14-19-18(21(26)15-22(19)27)8-3-1-2-4-10-23(28)29/h5-7,9,17-19,21-22,25-27H,1-4,8,10-15H2,(H,28,29)/t17-,18+,19+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50085917
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1
Show InChI InChI=1S/C23H36O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h3-5,8-9,18-22,24-26H,1-2,6-7,10-16H2,(H,27,28)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090138
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C24H38O6/c1-30-19-8-6-7-17(15-19)11-12-18(25)13-14-21-20(22(26)16-23(21)27)9-4-2-3-5-10-24(28)29/h6-8,15,18,20-23,25-27H,2-5,9-14,16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace [3H]-PGE-2 from human Prostaglandin E receptor EP1 isolated from CHO-KI cells (% of control ligand...


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090139
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1ccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)cc1
Show InChI InChI=1S/C24H38O6/c1-30-19-13-9-17(10-14-19)8-11-18(25)12-15-21-20(22(26)16-23(21)27)6-4-2-3-5-7-24(28)29/h9-10,13-14,18,20-23,25-27H,2-8,11-12,15-16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090130
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Ethyl-phenyl)-3-hydro...)
Show SMILES CCc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C25H40O5/c1-2-18-8-7-9-19(16-18)12-13-20(26)14-15-22-21(23(27)17-24(22)28)10-5-3-4-6-11-25(29)30/h7-9,16,20-24,26-28H,2-6,10-15,17H2,1H3,(H,29,30)/t20-,21+,22+,23-,24+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50085917
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1
Show InChI InChI=1S/C23H36O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h3-5,8-9,18-22,24-26H,1-2,6-7,10-16H2,(H,27,28)/t18-,19+,20+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090142
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES Cc1ccccc1CC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C24H38O5/c1-17-8-6-7-9-18(17)12-13-19(25)14-15-21-20(22(26)16-23(21)27)10-4-2-3-5-11-24(28)29/h6-9,19-23,25-27H,2-5,10-16H2,1H3,(H,28,29)/t19-,20+,21+,22-,23+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090139
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1ccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)cc1
Show InChI InChI=1S/C24H38O6/c1-30-19-13-9-17(10-14-19)8-11-18(25)12-15-21-20(22(26)16-23(21)27)6-4-2-3-5-7-24(28)29/h9-10,13-14,18,20-23,25-27H,2-8,11-12,15-16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090132
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Cyano-phenyl)-3-hydro...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C#N
Show InChI InChI=1S/C24H35NO5/c25-16-18-7-5-6-17(14-18)10-11-19(26)12-13-21-20(22(27)15-23(21)28)8-3-1-2-4-9-24(29)30/h5-7,14,19-23,26-28H,1-4,8-13,15H2,(H,29,30)/t19-,20+,21+,22-,23+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to displace [3H]-PGE-2 from human Prostaglandin E receptor EP3 isolated from CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090138
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C24H38O6/c1-30-19-8-6-7-17(15-19)11-12-18(25)13-14-21-20(22(26)16-23(21)27)9-4-2-3-5-10-24(28)29/h6-8,15,18,20-23,25-27H,2-5,9-14,16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090131
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(2-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1ccccc1F
Show InChI InChI=1S/C23H35FO5/c24-20-9-6-5-7-16(20)11-12-17(25)13-14-19-18(21(26)15-22(19)27)8-3-1-2-4-10-23(28)29/h5-7,9,17-19,21-22,25-27H,1-4,8,10-15H2,(H,28,29)/t17-,18+,19+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=87%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090143
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(F)c1
Show InChI InChI=1S/C23H35FO5/c24-17-7-5-6-16(14-17)10-11-18(25)12-13-20-19(21(26)15-22(20)27)8-3-1-2-4-9-23(28)29/h5-7,14,18-22,25-27H,1-4,8-13,15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090142
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-5-...)
Show SMILES Cc1ccccc1CC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C24H38O5/c1-17-8-6-7-9-18(17)12-13-19(25)14-15-21-20(22(26)16-23(21)27)10-4-2-3-5-11-24(28)29/h6-9,19-23,25-27H,2-5,10-16H2,1H3,(H,28,29)/t19-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090130
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Ethyl-phenyl)-3-hydro...)
Show SMILES CCc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C25H40O5/c1-2-18-8-7-9-19(16-18)12-13-20(26)14-15-22-21(23(27)17-24(22)28)10-5-3-4-6-11-25(29)30/h7-9,16,20-24,26-28H,2-6,10-15,17H2,1H3,(H,29,30)/t20-,21+,22+,23-,24+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090138
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES COc1cccc(CC[C@H](O)CC[C@H]2[C@H](O)C[C@H](O)[C@@H]2CCCCCCC(O)=O)c1
Show InChI InChI=1S/C24H38O6/c1-30-19-8-6-7-17(15-19)11-12-18(25)13-14-21-20(22(26)16-23(21)27)9-4-2-3-5-10-24(28)29/h6-8,15,18,20-23,25-27H,2-5,9-14,16H2,1H3,(H,28,29)/t18-,20+,21+,22-,23+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090132
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Cyano-phenyl)-3-hydro...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C#N
Show InChI InChI=1S/C24H35NO5/c25-16-18-7-5-6-17(14-18)10-11-19(26)12-13-21-20(22(27)15-23(21)28)8-3-1-2-4-9-24(29)30/h5-7,14,19-23,26-28H,1-4,8-13,15H2,(H,29,30)/t19-,20+,21+,22-,23+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from Prostaglandin E receptor EP1 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090143
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-5-(3-Fluoro-phenyl)-3-hydr...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(F)c1
Show InChI InChI=1S/C23H35FO5/c24-17-7-5-6-16(14-17)10-11-18(25)12-13-20-19(21(26)15-22(20)27)8-3-1-2-4-9-23(28)29/h5-7,14,18-22,25-27H,1-4,8-13,15H2,(H,28,29)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-U-46,619 from human TP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Thromboxane A2 receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50085914
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)
Show SMILES CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C20H38O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-19,21-23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,18-,19+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2<50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50035622
PNG
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 600n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=80%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50035622
PNG
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.30E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone=50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090136
PNG
((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)
Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-20,23-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,18+,19-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.00E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone=130%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090137
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)
Show SMILES CCCCC(C)(C)[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C22H42O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h16-20,23-25H,4-15H2,1-3H3,(H,26,27)/t16-,17-,18+,19-,20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<20%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090133
PNG
((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)
Show SMILES O[C@@H](CCc1cccc(c1)C(F)(F)F)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2<50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 85n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090137
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)
Show SMILES CCCCC(C)(C)[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C22H42O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h16-20,23-25H,4-15H2,1-3H3,(H,26,27)/t16-,17-,18+,19-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619<20%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50085910
PNG
((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)
Show SMILES O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 760n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=80%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50035622
PNG
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=95%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=100%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085911
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1cccc(Cl)c1
Show InChI InChI=1S/C22H33ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h5-7,12,16,18-21,24-26H,1-4,8-11,13-14H2,(H,27,28)/t16-,18-,19-,20+,21-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 9n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085914
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)
Show SMILES CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C20H38O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-19,21-23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,18-,19+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 5.00E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090133
PNG
((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)
Show SMILES O[C@@H](CCc1cccc(c1)C(F)(F)F)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 64n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=75%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50035622
PNG
((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 79n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50085911
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1cccc(Cl)c1
Show InChI InChI=1S/C22H33ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h5-7,12,16,18-21,24-26H,1-4,8-11,13-14H2,(H,27,28)/t16-,18-,19-,20+,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50085910
PNG
((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)
Show SMILES O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 10n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090133
PNG
((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)
Show SMILES O[C@@H](CCc1cccc(c1)C(F)(F)F)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2.10E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50085914
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)
Show SMILES CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C20H38O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-19,21-23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,18-,19+/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=100%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090140
PNG
(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)CCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C24H35F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h5-7,14,18-22,28-30H,1-4,8-13,15H2,(H,31,32)/t18-,19+,20+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50085911
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1cccc(Cl)c1
Show InChI InChI=1S/C22H33ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h5-7,12,16,18-21,24-26H,1-4,8-11,13-14H2,(H,27,28)/t16-,18-,19-,20+,21-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 8.00E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=90%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090136
PNG
((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)
Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-20,23-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,18+,19-,20-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 300n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=80%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50090136
PNG
((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)
Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-20,23-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,18+,19-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 24n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=95%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostanoid TP receptor


(Homo sapiens (Human))
BDBM50085910
PNG
((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)
Show SMILES O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2.40E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=100%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090136
PNG
((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)
Show SMILES CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-20,23-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,18+,19-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 90n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=150%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50090137
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)
Show SMILES CCCCC(C)(C)[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C22H42O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h16-20,23-25H,4-15H2,1-3H3,(H,26,27)/t16-,17-,18+,19-,20-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2<20%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50085910
PNG
((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)
Show SMILES O[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C22H29ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h1,3,5-7,10-12,16,18-21,24-26H,2,4,8-9,13-14H2,(H,27,28)/b3-1-,11-10+/t16-,18-,19-,20+,21-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 5.00E+3n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3(% of control ligand, sulprostone=75%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin F2-alpha receptor


(Homo sapiens (Human))
BDBM50090137
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)
Show SMILES CCCCC(C)(C)[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C22H42O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h16-20,23-25H,4-15H2,1-3H3,(H,26,27)/t16-,17-,18+,19-,20-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol<20%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1)


(Homo sapiens (Human))
BDBM50085911
PNG
(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)
Show SMILES O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O)COc1cccc(Cl)c1
Show InChI InChI=1S/C22H33ClO6/c23-15-6-5-7-17(12-15)29-14-16(24)10-11-19-18(20(25)13-21(19)26)8-3-1-2-4-9-22(27)28/h5-7,12,16,18-21,24-26H,1-4,8-11,13-14H2,(H,27,28)/t16-,18-,19-,20+,21-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.90E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP1 (% of control ligand, 17-phi-PGE2=100%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50090133
PNG
((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)
Show SMILES O[C@@H](CCc1cccc(c1)C(F)(F)F)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Show InChI InChI=1S/C24H31F3O5/c25-24(26,27)17-7-5-6-16(14-17)10-11-18(28)12-13-20-19(21(29)15-22(20)30)8-3-1-2-4-9-23(31)32/h1,3,5-7,12-14,18-22,28-30H,2,4,8-11,15H2,(H,31,32)/b3-1-,13-12+/t18-,19+,20+,21-,22+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
Prostaglandin E2 receptor


(Homo sapiens (Human))
BDBM50085914
PNG
(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)
Show SMILES CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O
Show InChI InChI=1S/C20H38O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-19,21-23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,18-,19+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>2.00E+4n/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Functional activity in RAT-1cells, transiently-transfected with human Prostaglandin E receptor EP3 (% of control ligand, sulprostone<50%)


Bioorg Med Chem Lett 10: 1519-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00273-0
BindingDB Entry DOI: 10.7270/Q28W3CJX
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%