Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50010915
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100105(2-(5-Bromo-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-N...)
Affinity DataIC50:  49nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100101(2-(5-Bromo-1-cyclopropylmethyl-2,2-dioxo-1,4-dihyd...)
Affinity DataIC50:  69nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100094(2-(5-Bromo-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-ben...)
Affinity DataIC50:  98nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100102(2-(5-Chloro-1-cyclopropylmethyl-2,2-dioxo-1,4-dihy...)
Affinity DataIC50:  110nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50:  120nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100096(2-(2,2-Dioxo-5-trifluoromethyl-1,4-dihydro-2H-2lam...)
Affinity DataIC50:  130nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100107(CHEMBL53345 | N-Hydroxy-2-(2-oxo-5-trifluoromethyl...)
Affinity DataIC50:  230nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100108(2-[5-Chloro-2,2-dioxo-1-(3-phenyl-propyl)-1,4-dihy...)
Affinity DataIC50:  290nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50:  460nMAssay Description:Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100100(2-(1-Butyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2lamb...)
Affinity DataIC50:  590nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100104(2-(2,2-Dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6...)
Affinity DataIC50:  760nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100099(2-(5-Fluoro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50:  870nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100103(2-(5-Fluoro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50:  870nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100098(CHEMBL54689 | N-Hydroxy-2-(2-oxo-1,4-dihydro-2H-qu...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100106(2-(1-Benzyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2lam...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition against endothelin-converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition against endothelin-converting enzyme.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100093((5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-ac...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition against neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed