Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50010990
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50094513(1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,2,2-...)
Affinity DataIC50:  200nMAssay Description:In vitro human CETP inhibitory activity of the compound was assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100997(1,1,1-Trifluoro-3-[(3-furan-2-yl-benzyl)-(3-phenox...)
Affinity DataIC50:  480nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101002(1,1,1-Trifluoro-3-[(4-fluoro-3-furan-2-yl-benzyl)-...)
Affinity DataIC50:  720nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particles to LDL acceptor p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100996(1,1,1-Trifluoro-3-[(3-furan-3-yl-benzyl)-(3-phenox...)
Affinity DataIC50:  910nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100999(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-thiophen-...)
Affinity DataIC50:  1.12E+3nMAssay Description:Binding affinity to 5-HT3 serotonin receptor in NG 108-15 neuroblastoma glioma cells using [3H]-GR-65,630 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101008(1,1,1-Trifluoro-3-[(3-furan-2-yl-4-methyl-benzyl)-...)
Affinity DataIC50:  3.96E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101007(1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(3-triflu...)
Affinity DataIC50:  4.08E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101000(3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50:  4.42E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101003(3-((3-ethoxybenzyl)(3-phenoxyphenyl)amino)-1,1,1-t...)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particles to LDL acceptor p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101006(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-pyridin-4...)
Affinity DataIC50:  6.24E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100998(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-pyrimidin...)
Affinity DataIC50:  6.72E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101009(1,1,1-Trifluoro-3-[[3-(1-methyl-1H-pyrrol-2-yl)-be...)
Affinity DataIC50:  6.79E+3nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101001(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-pyridin-3...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101005(1,1,1-Trifluoro-3-[[3-(3-methyl-pyridin-2-yl)-benz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101010(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-pyridin-2...)
Affinity DataIC50:  2.29E+4nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101004(1,1,1-Trifluoro-3-[(3-furan-2-yl-4-morpholin-4-yl-...)
Affinity DataIC50:  4.58E+4nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101000(3-((biphenyl-3-ylmethyl)(3-phenoxyphenyl)amino)-1,...)
Affinity DataIC50:  4.70E+4nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particles to LDL acceptor p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101002(1,1,1-Trifluoro-3-[(4-fluoro-3-furan-2-yl-benzyl)-...)
Affinity DataIC50:  4.90E+4nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particles to LDL acceptor p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100997(1,1,1-Trifluoro-3-[(3-furan-2-yl-benzyl)-(3-phenox...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of recombinant human CETP mediated transfer of [3H]-cholesteryl ester from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50100999(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-thiophen-...)
Affinity DataIC50:  8.30E+4nMAssay Description:In vitro human CETP inhibitory activity assessed by measuring the rate of [3H]-cholesteryl ester ([3H]-CE) from HDL donor particles to LDL acceptor p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed