Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50036991
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of dihydroorotate dehydrogenaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM4313((2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of EGF-dependent proliferation of human and guinea pig keratinocytes; range 7-15 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM4363((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethio...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of EGF-dependent proliferation of human and guinea pig keratinocytes; range 7-15 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50102251(5-[2-(1-{2-[4-(1-Hydroxy-1-methyl-ethyl)-phenylsul...)
Affinity DataKd:  0.0890nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataKd:  0.0650nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50369964(CALCIPOTRIENE | Calcipotriol)
Affinity DataKd:  0.310nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
Allergan

Curated by ChEMBL
LigandPNGBDBM50102248(5-[2-(1-{2-[4-(1-Hydroxy-1-methyl-ethyl)-phenoxy]-...)
Affinity DataKd:  0.0730nMAssay Description:Binding affinity to VDR receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed