Compile Data Set for Download or QSAR
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Found 184 Enz. Inhib. hit(s) with all data for entry = 50011107
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102331(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  5nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102377(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102352(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-hydroxy-phe...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102333(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(4-nitroph...)
Affinity DataKi:  10nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102364(3-(4-(4-chlorophenyl)piperazin-1-yl)-1-(naphthalen...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102371(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  10nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102362(1-Benzo[b]thiophen-3-yl-3-[4-(4-fluoro-2-methoxy-p...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102412(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  12nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102386(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(4-fluoro-2-me...)
Affinity DataKi:  13nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102337(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  16nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102350(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(5-methylt...)
Affinity DataKi:  17.5nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102374(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...)
Affinity DataKi:  17.5nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Affinity DataKi:  18nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102355(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  19nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102380(1-(3-(benzo[d][1,3]dioxol-5-yloxy)-3-phenylpropyl)...)
Affinity DataKi:  20nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102384(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-1-(5-methy...)
Affinity DataKi:  34nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102373(3-(4-(naphthalen-1-yl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  35nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102357(1-Benzo[b]thiophen-3-yl-3-[4-(4-chloro-2-methoxy-p...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102330(2-(4-(3-(benzo[b]thiophen-3-yl)-3-hydroxypropyl)pi...)
Affinity DataKi:  39nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102338(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
Affinity DataKi:  44nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102395(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...)
Affinity DataKi:  47.5nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102390(1-(benzo[b]thiophen-3-yl)-3-(4-(4-chlorophenyl)pip...)
Affinity DataKi:  50nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102389(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(4-nitroph...)
Affinity DataKi:  50nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102376(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  50nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102354(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-phenylprop...)
Affinity DataKi:  50nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102383(1-Phenyl-3-(4-pyridin-2-yl-piperazin-1-yl)-propan-...)
Affinity DataKi:  50nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102402(1-(3-(benzo[d][1,3]dioxol-5-yloxy)-3-(thiophen-3-y...)
Affinity DataKi:  55nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102405(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  60nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102348(3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-1-thiophen-...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102339(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-1-(5-methy...)
Affinity DataKi:  65nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102339(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-1-(5-methy...)
Affinity DataKi:  75nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102345(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  85nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102342(2-(4-(3-(2,5-dimethylthiophen-3-yl)-3-hydroxypropy...)
Affinity DataKi:  90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102365(1-(3-(4-methoxyphenoxy)-3-phenylpropyl)-4-(2-metho...)
Affinity DataKi:  90nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102405(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  95nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102343(1-(2,5-Dimethyl-thiophen-3-yl)-3-(4-naphthalen-1-y...)
Affinity DataKi:  100nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102328(1-(benzo[b]thiophen-3-yl)-3-(4-(naphthalen-1-yl)pi...)
Affinity DataKi:  100nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102338(1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-pi...)
Affinity DataKi:  105nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102410(1-(benzo[b]thiophen-3-yl)-3-(4-(2-hydroxyphenyl)pi...)
Affinity DataKi:  110nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102337(3-(4-(2-methoxyphenyl)piperazin-1-yl)-1-(thiophen-...)
Affinity DataKi:  112nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102351(3-(4-(2-chlorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  115nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102412(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  115nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102396(1-Phenyl-3-(4-pyrimidin-2-yl-piperazin-1-yl)-propa...)
Affinity DataKi:  120nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102339(3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-1-(5-methy...)
Affinity DataKi:  130nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102345(1-(2,5-Dimethyl-thiophen-3-yl)-3-[4-(2-methoxy-phe...)
Affinity DataKi:  130nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102406(3-(4-(4-fluorophenyl)piperazin-1-yl)-1-phenylpropa...)
Affinity DataKi:  145nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102346(1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-t...)
Affinity DataKi:  150nMAssay Description:Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50102359(1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)pi...)
Affinity DataKi:  150nMAssay Description:Affinity of the compound at dopamine D2 receptor from rat striatum using [3H]-spiroperidol as radioligand (For haloperidol Ki(nM)= 1.5+/-1.2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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