Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50011176
TargetLanosterol synthase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095601(CHEMBL25405 | [4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)...)
Affinity DataIC50:  58nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095599(CHEMBL25285 | {4-[4-(4,5-Dihydro-oxazol-2-yl)-benz...)
Affinity DataIC50:  90nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095598(CHEMBL70223 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)
Affinity DataIC50:  116nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095596(CHEMBL70222 | [4-(4-Bromo-benzenesulfonyl)-piperaz...)
Affinity DataIC50:  228nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed