Compile Data Set for Download or QSAR
maximum 50k data
Found 81 Enz. Inhib. hit(s) with all data for entry = 50011180
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103254(CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]- dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataKi:  4nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  9.30nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103247(10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...)
Affinity DataKi:  11nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103245(9-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-...)
Affinity DataKi:  18nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataKi:  37nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  53nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi:  95nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi:  95nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103245(9-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-...)
Affinity DataKi:  390nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103247(10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...)
Affinity DataKi:  493nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062433(9-Chloro-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-6...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi:  1.56E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi:  1.68E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103252(8-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity for glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi:  2.66E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataKi:  2.76E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103254(CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...)
Affinity DataKi:  3.07E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataKi:  3.12E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103247(10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...)
Affinity DataKi:  3.36E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataKi:  3.84E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103254(CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...)
Affinity DataKi:  3.91E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103247(10-Methoxy-2,2,4-trimethyl-5-(3-trifluoromethyl-ph...)
Affinity DataKi:  4.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103252(8-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H-...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103246(10-Methoxy-2,2,4-trimethyl-5-phenyl-2,5-dihydro-1H...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103254(CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity for progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103251(5-(3,5-Dichloro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataIC50:  1.30nMAssay Description:Transcriptional repression of IL-1 stimulated IL-6 expression in native cells compared to dexamethasoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50:  2.10nMAssay Description:Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50:  3.80nMAssay Description:Repression activity of GR ligand with interleukin-6 receptor in native cell assay using dexamethasone was determined as maximal potencyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataIC50:  4nMAssay Description:Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103254(CHEMBL317578 | Dimethyl-carbamic acid 3-(10-methox...)
Affinity DataIC50:  6nMAssay Description:Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataIC50:  8nMAssay Description:Transcriptional activation in CV-1 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103250(5-(3,5-Difluoro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataIC50:  9nMAssay Description:Transcriptional repression activity in HEP G2 cells expressing glucocorticoid receptor compared to dexamethasoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103249(10-Methoxy-2,2,4-trimethyl-5-(3-methylsulfanylmeth...)
Affinity DataIC50:  9nMAssay Description:Transcriptional activation in CV-1 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103248(5-(3,5-Dimethyl-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataIC50:  9.20nMAssay Description:Repression activity of GR ligand with interleukin-6 receptor in native cell assay using dexamethasone was determined as maximal potencyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103250(5-(3,5-Difluoro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataIC50:  10nMAssay Description:Transcriptional activation in CV-1 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50103250(5-(3,5-Difluoro-phenyl)-10-methoxy-2,2,4-trimethyl...)
Affinity DataIC50:  11nMAssay Description:Repression activity of GR ligand with interleukin-6 receptor in native cell assay using dexamethasone was determined as maximal potencyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 81 total ) | Next | Last >>
Jump to: