Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50011211
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103784(CHEMBL77638 | Phosphoric acid mono-(4-{2-acetylami...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103784(CHEMBL77638 | Phosphoric acid mono-(4-{2-acetylami...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103780(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)
Affinity DataIC50:  9.45E+4nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103780(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50:  3.03E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103787((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50:  3.70E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103785(CHEMBL263721 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)
Affinity DataIC50:  3.78E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103784(CHEMBL77638 | Phosphoric acid mono-(4-{2-acetylami...)
Affinity DataIC50:  4.41E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103782((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778(CHEMBL311114 | [5-{2-[1-(3-Carbamoyl-4-cyclohexylm...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103785(CHEMBL263721 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103783(CHEMBL308164 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103783(CHEMBL308164 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103788((5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103787((4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohex...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103781((4-{2-Acetylamino-2-[1-(3-carbamoyl-4-cyclohexylme...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103786((4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103785(CHEMBL263721 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103783(CHEMBL308164 | {4-[2-Acetylamino-2-(3-carbamoyl-4-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103779(CHEMBL430825 | Trifluoro-methanesulfonic acid 4-{2...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103779(CHEMBL430825 | Trifluoro-methanesulfonic acid 4-{2...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103780(CHEMBL308734 | [4-{2-Acetylamino-2-[(S)-1-(3-carba...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103779(CHEMBL430825 | Trifluoro-methanesulfonic acid 4-{2...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778(CHEMBL311114 | [5-{2-[1-(3-Carbamoyl-4-cyclohexylm...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Yes SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50103778(CHEMBL311114 | [5-{2-[1-(3-Carbamoyl-4-cyclohexylm...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of binding to Zap70 protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed