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Found 26 Enz. Inhib. hit(s) with all data for entry = 50035157
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104502(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104502(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  260nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through fibrin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104505(9-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104502(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  510nMAssay Description:Tissue plasminogen activator generation in plasmin was evaluated by measuring the ability to inhibit Plasminogen activator inhibitor-1 through comple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104511(7-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  520nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104514(5-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104504(8-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104503(CHEMBL87927 | Thiophene-2-carboxylic acid {4-[5-[1...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104518(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104507(7-{4-[3,6-Dioxo-5-[1-{4-[(thiophene-2-carbonyl)-am...)
Affinity DataIC50:  4.77E+3nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104524(CHEMBL312842 | N-{4-[5-[1-[5-(2-Dimethylamino-ethy...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104512(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104506(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104510(3-[1-(4-Bromo-phenyl)-meth-(Z)-ylidene]-6-[1-[5-(2...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104522(5-{4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-pipe...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104525(4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophe...)
Affinity DataIC50:  1.77E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104515(4-{4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-pipe...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104523(3-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophen-2...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104520(3-[1-(2-Bromo-phenyl)-meth-(Z)-ylidene]-6-[1-[5-(2...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104521(4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-ylidene]-piperaz...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104516(3-[1-(3-Chloro-phenyl)-meth-(Z)-ylidene]-6-[1-[5-(...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104519(3-[1-[5-(2-Dimethylamino-ethoxy)-thiophen-2-yl]-me...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104517(4-[5-[1-[5-(2-Dimethylamino-ethylsulfanyl)-thiophe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104513(3-[1-[5-(2-Diethylamino-ethylsulfanyl)-thiophen-2-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104509(3-[1-[5-(2-Dimethylamino-ethanesulfinyl)-thiophen-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Xenova

Curated by ChEMBL
LigandPNGBDBM50104508(CHEMBL86361 | {4-[3,6-Dioxo-5-[1-phenyl-meth-(Z)-y...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of compound against Plasminogen activator inhibitor-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed